Similar to cardiac tissue, juxtaglomerular cells harbor ?1 adrenergic receptors.
2.
Together, the macula densa and juxtaglomerular cells comprise the juxtaglomerular complex.
3.
The juxtaglomerular cells are also stimulated to release renin by signaling from the macula densa.
4.
Together, juxtaglomerular cells, extraglomerular mesangial cells and macula densa cells comprise the juxtaglomerular complex.
5.
The juxtaglomerular cells are very sensitive to endogenous pressors and control blood flow through the afferent arteriole.
6.
If less Na + is sensed by the macula densa, renin release by juxtaglomerular cells is increased.
7.
The juxtaglomerular cells in the afferent arteriole constrict, and juxtaglomerular cells in both the afferent and efferent arteriole decrease their renin secretion.
8.
The juxtaglomerular cells in the afferent arteriole constrict, and juxtaglomerular cells in both the afferent and efferent arteriole decrease their renin secretion.
9.
As such, an increase in sodium chloride concentration would result in vasoconstriction of afferent arterioles, and reduced paracrine stimulation of juxtaglomerular cells.
10.
Juxtaglomerular cells secrete renin in response to a drop in pressure detected by stretch receptors in the vascular walls, or when stimulated by macula densa cells.
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